Virus-like particle vaccines: immunology and formulation for clinical translation

Author:

Donaldson Braeden12ORCID,Lateef Zabeen3,Walker Greg F.4,Young Sarah L.2,Ward Vernon K.1ORCID

Affiliation:

1. Department of Microbiology and Immunology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand

2. Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand

3. Department of Pharmacology and Toxicology, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand

4. School of Pharmacy, University of Otago, Dunedin, New Zealand

Funder

Prostate Cancer Foundation of New Zealand

Freemasonry New Zealand

University of Otago

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,Molecular Medicine,Immunology

Reference175 articles.

1. Antigen delivery by virus-like particles for immunotherapeutic vaccination

2. Lachance P, Dionne M, Libman M, et al. Medicago, Inc. Immunogenicity of a quadrivalent virus-like particles (VLP) influenza vaccine in healthy adults. NCT02768805. 2016.

3. Sheldon E, Seiden DJ, Medicago, Inc. Immunogenicity, safety and tolerability of a plant-derived seasonal virus-like-particle quadrivalent influenza vaccine in adults. NCT02233816. 2016.

4. Acevedo-Flores M, Diaz C, Hoen B, et al. National Institute of Allergy and Infectious Diseases (NIAID). Trial for safety and immunogenicity of a chikungunya vaccine, VRC-CHKVLP059-00-VP, in healthy adults. NCT02562482. 2016.

5. Langley J, VBI Vaccines Inc. Study to evaluate safety, tolerability, and immunogenicity of candidate human cytomegalovirus vaccine in healthy adults. NCT02826798. 2016.

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