Affiliation:
1. Kemerovo State Medical University
2. Kemerovo State University
Abstract
Male infertility is an urgent medical and demographic threat worldwide, in particular in industrial regions suffering from environmental pollution. Here we performed an analysis of epidemiological studies and meta-analyses of prevalence, causes, and risk factors of male reproductive disorders. Among the well-defined risk factors determining male infertility are hormonal imbalance, sexually transmitted infections, other inflammatory diseases, hereditary mutations, and congenital malformations. Less studied causes of male infertility are acquired mutations and gene polymorphisms, immune disorders, oxidative stress, and chronic conditions. To date, there is no consensus on the contribution of lifestyle, bad habits, working environment, and climatic factors to male infertility. As such, 40-50% male infertility cases are characterized as idiopathic.
Publisher
Kemerovo State Medical University
Reference57 articles.
1. Agarwal A, Mulgund A, Hamada A, Chyatte MR. A unique view on male infertility around the globe. Reprod Biol Endocrinol. 2015;13:37. https://doi.org/10.1186/s12958-015-0032-1
2. Lebedev GS, Golubev NA, Shaderkin IA, Shaderkina VA, Apolikhin OI, Sivkova NV, Komarova VA. Male infertility in the Russian Federation: statistical data for 2000-2018. Experimental and clinical urology. 2019;(4):4- 12. (In Russ.). https://doi.org/10.29188/2222-8543-2019-11-4-4-12
3. Fillipov OS. Prichiny i faktory razvitiya besplodiya sredi naseleniya Sibiri. Epidemiologiya i infektsionnye bolezni. Epidemiology and infectious diseases. 2002;(3):47. (In Russ.).
4. Ustinova TA, Artymuk NV, Vlasova VV, Pyzhov AYa. Infertility in couples of Kemerovo region. Mother and baby in Kuzbass. 2010;1(40):37-39. (In Russ.).
5. Frolova NI, Belokrinitskaya TE, Anokhova LI, Kadalova NV, Lugovskaya OV, Yakimova YV, Ananjina DA, Turanova OV. Prevalence and characteristics of infertility in young women of reproductive age living in zabaykalsky district. Acta Biomed Sci (Bulletin of East Siberian scientific center SB RAMS). 2014;4(98):54-58. (In Russ.).
Cited by
3 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献