Association of nimodipine and choline alphoscerate in the treatment of cognitive impairment in patients with cerebral small vessel disease: study protocol for a randomized placebo-controlled trial—the CONIVaD trial
Author:
Funder
MDM Spa Company
Publisher
Springer Science and Business Media LLC
Subject
Geriatrics and Gerontology,Aging
Link
http://link.springer.com/content/pdf/10.1007/s40520-019-01229-z.pdf
Reference51 articles.
1. O’Brien JT, Erkinjuntti T, Reisberg B et al (2003) Vascular cognitive impairment. Lancet Neurol 2:89–98
2. Pantoni L (2010) Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges. Lancet Neurol 9:689–701
3. Wardlaw JM, Smith EE, Biessels GJ et al (2013) Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration. Lancet Neurol 12:822–838
4. Pantoni L (2004) Treatment of vascular dementia: evidence from trials with non-cholinergic drugs. J Neurol Sci 226:67–70
5. Smith EE, Cieslak A, Barber P et al (2017) Therapeutic strategies and drug development for vascular cognitive impairment. J Am Heart Assoc 1:1. https://doi.org/10.1161/JAHA.117.005568
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