Acute lesions in rats caused by 3-amino-1,2,4-benzotriazine-1,4-dioxide (SR 4233) or nitromin: a comparison with rates of reduction in microsomal systems from target organs

Author:

White Ian N. H.,Cahill Alan,Davies Adrian,Carthew Philip

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Toxicology,General Medicine

Reference21 articles.

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2. Bogdanffy MS (1990) Biotransformation enzymes in the rodent nas mucosa: the value of a histochemical approach. Environ Health Perspect 85: 177–186

3. Cahill A, White INH (1990) Reductive metabolism of 3-amino-1,2-benzotriazine-1,4-dioxide (SR 4233) and the induction of unscheduled DNA synthesis in rat and human derived cell lines. Carc nogenesis 11: 1407–1411

4. Costa AK, Baker MA, Brown JM, Trudell JR (1989) In vitro hepatotos icity of SR 4233 (3-amino 1,2,4-benzotriazine-1,4-dioxide), a hy poxic cytotoxin and potential antitumor agent. Cancer Res 925–929

5. Harlow E, Lane D (1988) Antibodies, a laboratory manual. Cold Sprit. Harbor Laboratory, p 505

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