Selected ellipticine derivatives, known to target topoisomerase II, suppress the alternative lengthening of telomere (ALT) pathway in telomerase

Selected ellipticine derivatives, known to target topoisomerase II, suppress the alternative lengthening of telomere (ALT) pathway in telomerase–negative cells

Published:2020-04-24 Issue:7 Volume:146 Page:1671-1676
ISSN:0171-5216
Container-title:Journal of Cancer Research and Clinical Oncology
language:en
Short-container-title:J Cancer Res Clin Oncol

Author:

Zencir Sevil,Hsieh Meng-Hsun,Hsu Joel-Sean,Ergun Yavuz,Chou Guan-Ling,Li Tsai-Kun,Teng Shu-Chun,Topcu Zeki

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology,General Medicine

Link

https://link.springer.com/content/pdf/10.1007/s00432-020-03213-x.pdf

Reference35 articles.

1. Basenko E, Topcu Z, McEachern MJ (2011) Recombination can either help maintain very short telomeres or generate longer telomeres via a roll-and-spread mechanism in yeast cells with weak telomerase activity. Eukaryot Cell 10:1131–1142

2. Blackburn EH (1992) Telomerases. Annu Rev Biochem 61:113–129

3. Blackburn EH, Epel ES, Lin J (2015) Human telomere biology: a contributory and interactive factor in aging, disease risks, and protection. Science 350:1193–1198

4. Blackburn EH, Greider CW, Szostak JW (2006) Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging. Nat Med 12:1133–1138

5. Bryan TM, Englezou A, Dalla-Pozza L, Dunham MA, Reddel RR (1997) Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines. Nat Med 3:1271–1274

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