Insights into Myocardial Perfusion PET Imaging: the Coronary Flow Capacity

Author:

Nappi Carmela,Ponsiglione Andrea,Falzarano Maria,Imbriaco Massimo,Klain Michele,Cuocolo Alberto

Abstract

Abstract Purpose of Review The present work summarizes the clinical relevance of coronary flow capacity (CFC) with an eye on future perspectives. Recent findings CFC concept has been recently introduced providing a comprehensive framework for coronary physiology evaluation. Summary It has been widely demonstrated that coronary artery disease (CAD) is a complex disease with a multifactorial etiology resulting from different pathogenic mechanisms. Cardiac positron emission tomography (PET) currently represents the gold standard for CAD assessment, providing absolute myocardial perfusion data including coronary flow reserve (CFR), calculated as the ratio of hyperemic to rest absolute myocardial blood flows. CFC can be obtained from dynamic PET images by plotting the primary stress perfusion data and CFR values for each pixel on a graph of predefined exact ranges. The routine evaluation of this parameter may add diagnostic and prognostic value to clinical and conventional imaging data.

Funder

Università degli Studi di Napoli Federico II

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Applied Microbiology and Biotechnology,Histology

Reference37 articles.

1. Cheema AN, Yanagawa B, Verma S, Bagai A, Liu S. Myocardial infarction with nonobstructive coronary artery disease (MINOCA): a review of pathophysiology and management. Curr Opin Cardiol. 2021;36(5):589–96. https://doi.org/10.1097/HCO.0000000000000886.

2. •Malakar AK, Choudhury D, Halder B, Paul P, Uddin A, Chakraborty S. A review on coronary artery disease, its risk factors, and therapeutics. J Cell Physiol. 2019;234(10):16812–16823. https://doi.org/10.1002/jcp.28350. (This review reveals the absolute global and regional trends of the CAD and the importance and contribution of CAD for global health.)

3. Ralapanawa U, Sivakanesan R. Epidemiology and the magnitude of coronary artery disease and acute coronary syndrome: a narrative review. J Epidemiol Glob Health. 2021;11(2):169–77. https://doi.org/10.2991/jegh.k.201217.001.

4. Nappi C, Ponsiglione A, Acampa W, Gaudieri V, Zampella E, Assante R, Cuocolo R, Mannarino T, Dell’Aversana S, Petretta M, Imbriaco M, Cuocolo A. Relationship between epicardial adipose tissue and coronary vascular function in patients with suspected coronary artery disease and normal myocardial perfusion imaging. Eur Heart J Cardiovasc Imaging. 2019;20(12):1379–87. https://doi.org/10.1093/ehjci/jez182.

5. Nappi C, Gaudieri V, Acampa W, Arumugam P, Assante R, Zampella E, Mannarino T, Mainolfi CG, Imbriaco M, Petretta M, Cuocolo A. Coronary vascular age: AN alternate means for predicting stress-induced myocardial ischemia in patients with suspected coronary artery disease. J Nucl Cardiol. 2019;26(4):1348–55. https://doi.org/10.1007/s12350-018-1191-1.

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