Abstract
AbstractAs detection of cancer and diabetes diseases has captured a great attention in the field of biosensing, many ways were introduced to detect these diseases with high accuracy. This paper presents a novel use of zinc selenide (ZnSe) semiconductor material to enhance the sensitivity of a conventional Ag-based surface plasmon resonance biosensor. The proposed sensor structure is simple (BK7 prism/Ag/ZnSe), cost-effective, and easy to design and fabricate. The sensor is tested in the detection of different cancerous cells in human blood, showing an excellent sensitivity of 359$$^\circ$$
∘
/RIU. In addiion, it is tested to detect various glucose levels in human urine, and it provides a very high performance with a sensitivity of 366.6$$^\circ$$
∘
/RIU, which is 70% better than that of a similar reported work. Thus, the proposed biosensor is capable efficiently to detect various kinds of cancer cells and different glucose concentrations in urine.
Funder
Arab Academy for Science, Technology & Maritime Transport
Publisher
Springer Science and Business Media LLC
Subject
Electrical and Electronic Engineering,Atomic and Molecular Physics, and Optics,Electronic, Optical and Magnetic Materials
Reference36 articles.
1. Akib, T.B.A., Mou, S.F., Rahman, M.M., Rana, M.M., Islam, M.R., Mehedi, I.M., Mahmud, M.A.P., Kouzani, A.Z.: Design and numerical analysis of a graphene-coated SPR biosensor for rapid detection of the novel coronavirus. Sensors 21, 3491 (2021)
2. Bellassai, N., D’Agata, R., Jungbluth, V., Spoto, G.: Surface plasmon resonance for biomarker detection: advances in non-invasive cancer diagnosis. Front. Chem. 7, 570 (2019)
3. Brahmachari, K., Ray, M.: Effect of prism material on design of surface plasmon resonance sensor by admittance loci method. Front. Optoelectron. 6(2), 185–193 (2013)
4. Basal Cell Carcinoma: Overview.: https://www.skincancer.org/skin-cancer-information/basal-cell-carcinoma. Accessed Mar. 2022 (2022)
5. Chen, W.P., Chen, J.M.: Use of surface plasma waves for determination of the thickness and optical constants of thin metallic films. J. Opt. Soc. Am. 71(2), 189–191 (1981)
Cited by
20 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献