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Liraglutide Attenuates Myocardial Ischemia/Reperfusion Injury Through the Inhibition of Necroptosis by Activating GLP-1R/PI3K/Akt Pathway

  • Published:2023-03-19 Issue: Volume: Page:
  • ISSN:1530-7905
  • Container-title:Cardiovascular Toxicology
  • language:en
  • Short-container-title:Cardiovasc Toxicol

Author:

Zhou Gang,Wu Hui,Yang Jian,Ye Ming,Liu Di,Li Yunzhao,Zhang Dong,Zhang Jing,Yang Qingzhuo,Liu Yanfang

Funder

National Natural Science Foundation of China

Natural Science Foundation of Hubei Provience

Publisher

Springer Science and Business Media LLC

Subject

Cardiology and Cardiovascular Medicine,Toxicology,Molecular Biology

Reference44 articles.

1. Virani, S. S., Alonso, A., Benjamin, E. J., Bittencourt, M. S., Callaway, C. W., Carson, A. P., Chamberlain, A. M., Chang, A. R., Cheng, S., Delling, F. N., Djousse, L., Elkind, M. S. V., Ferguson, J. F., Fornage, M., Khan, S. S., Kissela, B. M., Knutson, K. L., Kwan, T. W., Lackland, D. T., & Tsao, C. W. (2020). Heart Disease and Stroke Statistics-2020 Update: A report from the American Heart Association. Circulation, 141(9), e139–e596. https://doi.org/10.1161/CIR.0000000000000757

2. Yellon, D. M., & Hausenloy, D. J. (2007). Myocardial reperfusion injury. The New England Journal of Medicine, 357(11), 1121–1135. https://doi.org/10.1056/NEJMra071667

3. Amani, H., Habibey, R., Hajmiresmail, S. J., Latifi, S., Pazoki-Toroudi, H., & Akhavan, O. (2017). Antioxidant nanomaterials in advanced diagnoses and treatments of ischemia reperfusion injuries. Journal of Materials Chemistry B, 5(48), 9452–9476. https://doi.org/10.1039/c7tb01689a

4. Wang, J. X., Jiao, J. Q., Li, Q., Long, B., Wang, K., Liu, J. P., Li, Y. R., & Li, P. F. (2011). miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1. Nature Medicine, 17(1), 71–78. https://doi.org/10.1038/nm.2282

5. Oerlemans, M. I., Liu, J., Arslan, F., den Ouden, K., van Middelaar, B. J., Doevendans, P. A., & Sluijter, J. P. (2012). Inhibition of RIP1-dependent necrosis prevents adverse cardiac remodeling after myocardial ischemia-reperfusion in vivo. Basic Research in Cardiology, 107(4), 270. https://doi.org/10.1007/s00395-012-0270-8
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