Comparison of renal excretion of pethidine (meperidine) and its metabolites in old and young patients

Author:

Odar-Cederl�f I.,Bor�us L. O.,Bondesson U.,Holmberg L.,Heyner L.

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Reference12 articles.

1. Asatoor AM, London DR, Milne MD, Simenhoff ML (1963) The excretion of pethidine and its derivates. Br J Pharmacol 20: 285?298

2. Crooks J, O'Malley K, Stevenson IH (1976) Pharmacokinetics in the elderly. Clin Pharmacokinet 1: 280?296

3. Dahlström BE, Paalzow LK, Lindberg C, Bogentoft C (1979) Pharmacokinetics and analgesic effect of pethidine (meperidine) and its metabolites in the rat. Drug Metab Dispos 7: 108?112

4. Davies DF, Shock NW (1950) Age changes in glomerular filtration rate, effective renal flow and tubular excretory capacity in adult males. J Clin Invest 29: 496?507

5. Greenblatt DJ, Sellers EM, Shader RI (1982) Drug disposition in old age. N Engl J Med 306: 1081?1088

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