Visualizing Fluid Flows via Regularized Optimal Mass Transport with Applications to Neuroscience

Author:

Chen XinanORCID,Tran Anh Phong,Elkin Rena,Benveniste Helene,Tannenbaum Allen R.

Abstract

AbstractThe regularized optimal mass transport (rOMT) problem adds a diffusion term to the continuity equation in the original dynamic formulation of the optimal mass transport (OMT) problem proposed by Benamou and Brenier. We show that the rOMT model serves as a powerful tool in computational fluid dynamics for visualizing fluid flows in the glymphatic system. In the present work, we describe how to modify the previous numerical method for efficient implementation, resulting in a significant reduction in computational runtime. Numerical results applied to synthetic and real-data are provided.

Funder

Cure Alzheimer’s Fund

Army Research Office

Foundation for the National Institutes of Health

AFOSR

Publisher

Springer Science and Business Media LLC

Subject

Computational Theory and Mathematics,General Engineering,Theoretical Computer Science,Software,Applied Mathematics,Computational Mathematics,Numerical Analysis

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