A kinome-targeted RNAi-based screen links FGF signaling to H2AX phosphorylation in response to radiation

Author:

Benzina Sami,Pitaval Amandine,Lemercier Claudie,Lustremant Celine,Frouin Vincent,Wu Ning,Papine Alexandre,Soussaline Françoise,Romeo Paul-Henri,Gidrol Xavier

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Cellular and Molecular Neuroscience,Pharmacology,Molecular Biology,Molecular Medicine

Reference60 articles.

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2. Fuks Z, Persaud RS, Alfieri A et al (1994) Basic fibroblast growth factor protects endothelial cells against radiation-induced programmed cell death in vitro and in vivo. Cancer Res 54:2582–2590

3. Pena LA, Fuks Z, Kolesnick RN (2000) Radiation-induced apoptosis of endothelial cells in the murine central nervous system: protection by fibroblast growth factor and sphingomyelinase deficiency. Cancer Res 60:321–327

4. Gu Q, Wang D, Wang X et al (2004) Basic fibroblast growth factor inhibits radiation-induced apoptosis of HUVECs. I. The PI3K/AKT pathway and induction of phosphorylation of BAD. Radiat Res 161:692–702

5. Gu Q, Wang D, Wang X et al (2004) Basic fibroblast growth factor inhibits radiation-induced apoptosis of HUVECs. II. The RAS/MAPK pathway and phosphorylation of BAD at serine 112. Radiat Res 161:703–711

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