Heterologous expression of an acid phosphatase gene and phosphate limitation leads to substantial production of chicoric acid in Echinacea purpurea transgenic hairy roots
Author:
Funder
Tarbiat Modares University
Publisher
Springer Science and Business Media LLC
Subject
Plant Science,Genetics
Link
http://link.springer.com/content/pdf/10.1007/s00425-019-03317-w.pdf
Reference71 articles.
1. Abbasi BH, Liu R, Saxena PK, Liu CZ (2009) Cichoric acid production from hairy root cultures of Echinacea purpurea grown in a modified airlift bioreactor. J Chem Technol Biotechnol 84:1697–1701. https://doi.org/10.1002/jctb.2233
2. Azay-Milhau J, Ferrare K, Leroy J, Ferrare K, Leroy J, Aubaterre J, Tournier M, Lajoix AD, Tousch D (2013) Antihyperglycemic effect of a natural chicoric acid extract of chicory (Cichorium intybus L.): a comparative in vitro study with the effects of caffeic and ferulic acids. J Ethnopharmacol 150:755–760. https://doi.org/10.1016/j.jep.2013.09.046
3. Bais HP, Sudha G, George J, Ravishankar GA (2001) Influence of exogenous hormones on growth and secondary metabolite production in hairy root cultures of Cichorium intybus L. cv. Lucknow local. In Vitro Cell Dev Biol 37:293–299. https://doi.org/10.1007/s11627-001-0052-8
4. Balague C, Wilson G (1982) Growth and alkaloid biosynthesis by cell suspensions of Catharanthus roseus in a chemostat under sucrose and phosphate limiting conditions. Physiol Veg 20:515–522
5. Banerjee S, Singh S, Pandey P (2017) “Hairy Root” technology: an emerging arena for heterologous expression of biosynthetic pathway genes in medicinal plants. In: Jha S (ed) Transgenesis and secondary metabolism. Springer, Berlin, pp 295–322. https://doi.org/10.1007/978-3-319-28669-3
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