A novel antitumor mechanism of triptonide in colorectal cancer: inducing ferroptosis via the SLC7A11/GPX4 axis
Author:
Funder
Natural Science Foundation of Ningxia Province
Publisher
Springer Science and Business Media LLC
Link
https://link.springer.com/content/pdf/10.1007/s10142-024-01402-2.pdf
Reference33 articles.
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2. Chang Z, Qin W, Zheng H, Schegg K, Han L, Liu X, Wang Y, Wang Z (2021) Triptonide is a reversible non-hormonal male contraceptive agent in mice and non-human primates. Nat Commun 12:1253. https://doi.org/10.1038/s41467-021-21517-5
3. Chen X, Li J, Kang R, Klionsky DJ, Tang D (2021) Ferroptosis: machinery and regulation. Autophagy 17:2054–2081. https://doi.org/10.1080/15548627.2020.1810918
4. Chen H, Qi Q, Wu N, Wang Y, Feng Q, Jin R, Jiang L (2022) Aspirin promotes RSL3-induced ferroptosis by suppressing mTOR/SREBP-1/SCD1-mediated lipogenesis in PIK3CA-mutant colorectal cancer. Redox Biol 55:102426. https://doi.org/10.1016/j.redox.2022.102426
5. Cheng Q, Chen M, Liu M, Chen X, Zhu L, Xu J, Xue J, Wu H, Du Y (2022) Semaphorin 5A suppresses ferroptosis through activation of PI3K-AKT-mTOR signaling in rheumatoid arthritis. Cell Death Dis 13:608. https://doi.org/10.1038/s41419-022-05065-4
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