Phase I study of mitonafide in solid tumors

Author:

Llombart Manuel,Poveda Andr�s,Forner Ernesto,Fern�ndez-Martos Carlos,Gaspar Crist�bal,Mu�oz Miguel,Olmos Teresa,Ruiz Amparo,Soriano Virtudes,Benavides Ana,Martin Miguel,Schlick Erich,Guillem Vicente

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,Oncology

Reference6 articles.

1. Braña MF, Castellano JM, Roldán CM: Synthesis and mode(s) of action of a new series of imide derivatives of 3-nitro-1, 8-naphtalic acid. Cancer Chemother Pharmacol 4: 61?66, 1980

2. Braña MF, Martínez Sanz A, Castellano JM, Martínez Roldán C, Roldán C: Synthesis and cytostatic activity of benz (de) isoquinolin-1, 3-diones. Structure-activity relationships. Eur J Med Chem 16(3):207?212, 1981

3. Nishio A, Uyeki EM: Induction of DNA strand breaks and chromosome abnormalities by an imide derivative of 3-nitro-1, 8-naphthalic acid (mitonafide) in chinese hamster ovary cells. J Natl Cancer Inst 70:1097?1102, 1983

4. Sinha BK, Strong J: Mechanism of DNA strand breaks by mitonafide, an imide derivative of 3-nitro-1, 8-naphthalic acid. Biochem Pharmacol 34:3845?3852, 1985

5. Miller AB, Hoogstraten B, Staquet M: Reporting results of cancer treatment. Cancer 47:207?214, 1981

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