A Phase II, Single-Center, Randomized, Double-Blind, Placebo-Controlled Study of the Safety and Therapeutic Efficacy of Intranasal Glulisine in Amnestic Mild Cognitive Impairment and Probable Mild Alzheimer’s Disease-Reference-Cited by-同舟云学术

A Phase II, Single-Center, Randomized, Double-Blind, Placebo-Controlled Study of the Safety and Therapeutic Efficacy of Intranasal Glulisine in Amnestic Mild Cognitive Impairment and Probable Mild Alzheimer’s Disease

Published:2021-03-15 Issue:5 Volume:38 Page:407-415
ISSN:1170-229X
Container-title:Drugs & Aging
language:en
Short-container-title:Drugs Aging

Author:

Rosenbloom Michael^ORCID,Barclay Terry R.,Kashyap Bhavani,Hage Lyndsay,O’Keefe Lauren R.,Svitak Aleta,Pyle Maria,Frey William,Hanson Leah R.

Funder

HealthPartners Research Institute

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Geriatrics and Gerontology

Link

https://link.springer.com/content/pdf/10.1007/s40266-021-00845-7.pdf

Reference18 articles.

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3. Laws SM, Gaskin S, Woodfield A, et al. Insulin resistance is associated with reductions in specific cognitive domains and increases in CSF tau in cognitively normal adults. Sci Rep. 2017;7(1):9766.

4. Yarchoan M, Toledo JB, Lee EB, et al. Abnormal serine phosphorylation of insulin receptor substrate 1 is associated with tau pathology in Alzheimer’s disease and tauopathies. Acta Neuropathol. 2014;128(5):679–89.

5. Ott A, Stolk RP, van Harskamp F, et al. Diabetes mellitus and the risk of dementia: the rotterdam study. Neurology. 1999;53(9):1937–42.

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