Interactions between kappa and mu opioid receptor agonists: effects of the ratio of drugs in mixtures

Author:

Minervini Vanessa,Lu Hannah Y.,Padarti Jahnavi,Osteicoechea Daniela C.,France Charles P.ORCID

Funder

National Institute on Drug Abuse

Welch Foundation

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology

Reference47 articles.

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2. Briggs SL, Rech RH, Sawyer (1998) Kappa antinociceptive activity of spiradoline in the cold-water tail-flick assay in rats. Pharmacol Biochem Behav 60:467–472

3. Dart RC, Surratt HL, Cicero TJ, Parrino MW, Severtson SG, Bucher-Bartelson B, Green JL (2015) Trends in opioid analgesia abuse and mortality in the United States. N Engl J Med 372:241–248

4. Dosaka-Akita K, Tortella FC, Holaday JW, Long JB (1993) The kappa opioid agonist U-50,488H antagonizes respiratory effects of mu opioid receptor agonists in conscious rats. J Pharmacol Exp Ther 264:631–637

5. Dykstra LA, Gmerek DE, Winger G, Woods JE (1987) Kappa opioids in rhesus monkeys. I. Diuresis, sedations, analgesia, and discriminative stimulus effects. J Pharmacol Exp Ther 242:413–420

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