Rescuing Canavan disease: engineering the wrong cell at the right time
Author:
Publisher
Wiley
Subject
Genetics (clinical),Genetics
Link
http://link.springer.com/article/10.1007/s10545-017-0038-2/fulltext.html
Reference7 articles.
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3. Baslow MH, Guilfoyle DN (2016) Evidence that N-acetylaspartylglutamate is the astrocyte-targeted neurovascular coupling agent that regulates slow tonic control of brain blood flow. J Glycomics Metab 1(1):1–12
4. Baslow MH, Suckow R, Sapirstein V, Hungund BL (1999) Expression of aspartoacylase activity in cultured rat macroglial cells is limited to oligodendrocytes. J Mol Neurosci 13:47–53
5. Gessler DJ, Li D, Xu H, Su Q, Sanmiguel J, Tuncer S, Moore C, King J, Matalon R, Gao G (2017) Redirecting N-acetylaspartate metabolism in the central nervous system normalizes myelination and rescues Canavan disease. JCI Insight. doi: 10.1172/jci.insight.90807
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