Enzyme Engineering Strategies for the Bioenhancement of l-Asparaginase Used as a Biopharmaceutical
Author:
Funder
FAPESP-UFRO
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Pharmacology,General Medicine,Biotechnology
Link
https://link.springer.com/content/pdf/10.1007/s40259-023-00622-5.pdf
Reference177 articles.
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2. Ardalan N, Mirzaie S, Sepahi AA, Khavari-Nejad RA. Novel mutant of Escherichia coli asparaginase II to reduction of the glutaminase activity in treatment of acute lymphocytic leukemia by molecular dynamics simulations and QM-MM studies. Med Hypotheses. 2018;112:7–17. https://doi.org/10.1016/j.mehy.2018.01.004.
3. Arnold FH. Directed evolution: bringing new chemistry to life. Angew Chem Int Ed. 2018;57(16):4143–8.
4. Asselin BL. The three asparaginases. In: Drug resistance in leukemia and lymphoma III. New York: Springer; 1999. p. 621–9.
5. Avramis VI. Asparaginases: biochemical pharmacology and modes of drug resistance. Anticancer Res. 2012;32(7):2423–37.
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