Author:
Schumann Vanessa,Lein F. Nicolas,Börner Richard
Abstract
AbstractSingle-molecule fluorescence spectroscopy is an established method for investigating biomolecular structures and their dynamics. Sample preparation is crucial for the success of these experiments and consists of several steps that need to be handled with care by the experimenter. These manual steps are not only time consuming and error prone, but complicate high-throughput applications. To address this challenge, we have introduced a pressure-controlled microfluidic system for automated sample preparation in single-molecule spectroscopy.
Publisher
Springer Science and Business Media LLC