Adjusted Indirect Treatment Comparison of Progression-Free Survival with D-Rd and VRd Based on MAIA and SWOG S0777 Individual Patient-Level Data

Author:

Durie Brian G. M.,Kumar Shaji K.,Ammann Eric M.,Fu Alex Z.,Kaila Shuchita,Lam Annette,Usmani Saad Z.,Facon Thierry

Funder

Janssen Global Services, LLC

Publisher

Springer Science and Business Media LLC

Reference27 articles.

1. Dimopoulos MA, Moreau P, Terpos E, et al. Multiple myeloma: EHA-ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Hemasphere. 2021;5(2):e528.

2. Referenced with permission from the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) for Multiple Myeloma V2.2024. © National Comprehensive Cancer Network, Inc. 2023. All rights reserved. Accessed Mar 5, 2024. To view the most recent and complete version of the guidelines, go online to NCCN.org. NCCN makes no warranties or any kind whatsoever regarding their content, use or application and disclaims any responsibility for their application or use in any way.

3. Kumar SK, Moreau P, Bahlis N, et al. Daratumumab plus lenalidomide and dexamethasone (D-Rd) versus lenalidomide and dexamethasone (Rd) alone in transplant ineligible patients with newly diagnosed multiple myeloma (NDMM): updated analysis of the phase 3 MAIA study. Presented at: 64th American Society of Hematology (ASH) Annual Meeting & Exposition; December 10–13, 2022; New Orleans, LA.

4. Durie BG, Hoering A, Abidi MH, et al. Bortezomib with lenalidomide and dexamethasone versus lenalidomide and dexamethasone alone in patients with newly diagnosed myeloma without intent for immediate autologous stem-cell transplant (SWOG S0777): a randomised, open-label, phase 3 trial. Lancet. 2017;389(10068):519–27.

5. Facon T, Kumar SK, Plesner T, et al. Daratumumab, lenalidomide, and dexamethasone versus lenalidomide and dexamethasone alone in newly diagnosed multiple myeloma (MAIA): overall survival results from a randomised, open-label, phase 3 trial. Lancet Oncol. 2021;22(11):1582–96.

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