New Insights into Active Site Conformation Dynamics of E. coli PNP Revealed by Combined H/D Exchange Approach and Molecular Dynamics Simulations-Reference-Cited by-同舟云学术

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New Insights into Active Site Conformation Dynamics of E. coli PNP Revealed by Combined H/D Exchange Approach and Molecular Dynamics Simulations

Published:2015-09-03 Issue:1 Volume:27 Page:73-82
ISSN:1044-0305
Container-title:Journal of the American Society for Mass Spectrometry
language:en
Short-container-title:J. Am. Soc. Mass Spectrom.

Author:

Kazazić Saša¹,Bertoša Branimir²,Luić Marija¹,Mikleušević Goran¹,Tarnowski Krzysztof³,Dadlez Michal³,Narczyk Marta⁴,Bzowska Agnieszka⁴

Affiliation:

1. Division of Physical Chemistry, Ruđer Bošković Institute, Zagreb, Croatia

2. Division of Physical Chemistry, Faculty of Science at University of Zagreb, Zagreb, Croatia

3. Institute of Biochemistry and Biophysics Department, Polish Academy of Science, Warsaw, Poland

4. Division of Biophysics, Institute of Experimental Physics, University of Warsaw, Warsaw, Poland

Publisher

American Chemical Society (ACS)

Subject

Spectroscopy,Structural Biology

Link

http://link.springer.com/content/pdf/10.1007/s13361-015-1239-2.pdf

Reference59 articles.

1. Exploring and exploiting allostery: Models, evolution, and drug targeting

2. 50 years of allosteric interactions: the twists and turns of the models

3. Understanding allosteric and cooperative interactions in enzymes

4. The ensemble nature of allostery

5. Variations on the theme: allosteric control in hemoglobin

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1. SAXS Analysis and Characterization of Anticancer Activity of PNP-UDP Family Protein from Putranjiva roxburghii;The Protein Journal;2022-06

2. Single tryptophan Y160W mutant of homooligomeric E. coli purine nucleoside phosphorylase implies that dimers forming the hexamer are functionally not equivalent;Scientific Reports;2021-05-27

3. Binding of dipeptidyl peptidase III to the oxidative stress cell sensor Kelch-like ECH-associated protein 1 is a two-step process;Journal of Biomolecular Structure and Dynamics;2020-08-18

4. Crystallographic snapshots of ligand binding to hexameric purine nucleoside phosphorylase and kinetic studies give insight into the mechanism of catalysis;Scientific Reports;2018-10-18

5. Part-of-the-sites binding and reactivity in the homooligomeric enzymes – facts and artifacts;Archives of Biochemistry and Biophysics;2018-03

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