Endotoxin does not alter the pharmacokinetics of micafungin, but it impairs biliary excretion of micafungin via multidrug resistance-associated protein 2 (ABCC2/Mrp2) in rats

Author:

Noda Takayuki,Abe Fumie,Kato Miki,Saito Hiroko,Hasegawa Takaaki,Ueyama Jun,Katoh Miki,Nadai Masayuki

Publisher

Elsevier BV

Subject

Infectious Diseases,Pharmacology (medical),Microbiology (medical)

Reference32 articles.

1. Metabolites of micafungin in rats and dogs;Kaneko;Jpn J Chemother,2002

2. Distribution and excretion after intravenous dosing of [14C] micafungin to rats;Yamato;Jpn J Chemother,2002

3. Involvement of multidrug resistance-associated protein 2 (ABCC2/Mrp2) in biliary excretion of micafungin in rats;Abe;Life Sci,2008

4. Concomitant tacrolimus and micafungin pharmacokinetics in healthy volunteers;Hebert;J Clin Pharmacol,2005

5. Concomitant cyclosporine and micafungin pharmacokinetics in healthy volunteers;Hebert;J Clin Pharmacol,2005

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1. Equinocandinas: aspectos aplicados de la farmacología;Revista Iberoamericana de Micología;2016-07

2. Intracellular concentrations of anidulafungin in different compartments of the peripheral blood;International Journal of Antimicrobial Agents;2013-04

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