Should we treat mild hypotension in septic patients in the absence of peripheral tissue hypoperfusion?

Author:

Lavillegrand Jean-Rémi,Dumas Guillaume,Bigé Naïke,Zafimahazo Daniel,Guidet Bertrand,Maury Eric,Ait-Oufella HafidORCID

Publisher

Springer Science and Business Media LLC

Subject

Critical Care and Intensive Care Medicine

Reference5 articles.

1. Rhodes A, Evans LE, Alhazzani W, Levy MM, Antonelli M, Ferrer R, Kumar A, Sevransky JE, Sprung CL, Nunnally ME, Rochwerg B, Rubenfeld GD, Angus DC, Annane D, Beale RJ, Bellinghan GJ, Bernard GR, Chiche JD, Coopersmith C, De Backer DP, French CJ, Fujishima S, Gerlach H, Hidalgo JL, Hollenberg SM, Jones AE, Karnad DR, Kleinpell RM, Koh Y, Lisboa TC, Machado FR, Marini JJ, Marshall JC, Mazuski JE, McIntyre LA, McLean AS, Mehta S, Moreno RP, Myburgh J, Navalesi P, Nishida O, Osborn TM, Perner A, Plunkett CM, Ranieri M, Schorr CA, Seckel MA, Seymour CW, Shieh L, Shukri KA, Simpson SQ, Singer M, Thompson BT, Townsend SR, Van der Poll T, Vincent JL, Wiersinga WJ, Zimmerman JL, Dellinger RP (2017) Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock: 2016. Intensive Care Med 43(3):304–377. https://doi.org/10.1007/s00134-017-4683-6

2. Maheshwari K, Nathanson BH, Munson SH, Khangulov V, Stevens M, Badani H, Khanna AK, Sessler DI (2018) The relationship between ICU hypotension and in-hospital mortality and morbidity in septic patients. Intensive Care Med. https://doi.org/10.1007/s00134-018-5218-5

3. Ait-Oufella H, Bakker J (2016) Understanding clinical signs of poor tissue perfusion during septic shock. Intensive Care Med 42(12):2070–2072. https://doi.org/10.1007/s00134-016-4250-6

4. Ince C (2005) The microcirculation is the motor of sepsis. Crit Care 9(Suppl 4):S13–S19

5. Dunser MW, Takala J, Brunauer A, Bakker J (2013) Re-thinking resuscitation: leaving blood pressure cosmetics behind and moving forward to permissive hypotension and a tissue perfusion-based approach. Crit Care 17(5):326. https://doi.org/10.1186/cc12727

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