Plantago major Ameliorates Adriamycin–Induced Renal Fibrosis via Down-Regulation of TGF-β and Collagen IV Expression

Author:

Khajavi Rad Abolfazl,Shahraki Samira,Naji Ebrahimi Yazd Zohreh,Ebrahimzadeh Bideskan Alireza,Hedayati-Moghadam Mahdiyeh,Samadi Noshahr Zahra,Hosseinian Sara

Funder

Mashhad University of Medical Sciences

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Mathematics,General Earth and Planetary Sciences,General Agricultural and Biological Sciences,General Chemistry

Reference18 articles.

1. Katzung BG (2012) Basic and clinical pharmacology, 12th edn. Mc Graw Hill, New York

2. Berlin V, Haseltine W (1981) Reduction of adriamycin to a semiquinone-free radical by NADPH cytochrome P-450 reductase produces DNA cleavage in a reaction mediated by molecular oxygen. J Biol Chem 256:4747–4756

3. EntezariHeravi N, Hosseinian S, NajiEbrahimi Yazd Z, Shafei MN, EbrahimzadehBideskan A, Shahraki S, SamadiNoshahr Z, Motejadded F, Beheshti F, Mohebbati R, Parhizgar S, Khajavi RA (2018) Doxorubicin-induced renal inflammation in rats: protective role of Plantago major. Avicenna J Phytomed 8:179

4. Gomez-Flores R, Calderon C, Scheibel L, Tamez-Guerra P, Rodriguez-Padilla C, Tamez-Guerra R, Weber R (2000) Immunoenhancing properties of Plantago major leaf extract. Phytother Res 14:617–622

5. Kim DR et al (2017) Ameliorating effect of gemigliptin on renal injury in murine adriamycin-induced nephropathy. BioMed Res Int 2017:1–10

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