Tumor-associated Endo180 requires stromal-derived LOX to promote metastatic prostate cancer cell migration on human ECM surfaces

Author:

Caley Matthew P.,King Helen,Shah Neel,Wang Kai,Rodriguez-Teja Mercedes,Gronau Julian H.,Waxman Jonathan,Sturge Justin

Funder

The Rosetrees Trust

Association for International Cancer Research

Prostate Cancer UK

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology,General Medicine

Reference65 articles.

1. Sturge J, Caley MP, Waxman J (2011) Bone metastasis in prostate cancer: emerging therapeutic strategies. Nat Rev Clin Oncol 8(6):357–368. doi: 10.1038/nrclinonc.2011.67

2. Reichert JC, Quent VMC, Burke LJ, Stansfield SH, Clements JA, Hutmacher DW (2010) Mineralized human primary osteoblast matrices as a model system to analyse interactions of prostate cancer cells with the bone microenvironment. Biomaterials 31(31):7928–7936. doi: 10.1016/j.biomaterials.2010.06.055

3. Hesami P, Holzapfel BM, Taubenberger A, Roudier M, Fazli L, Sieh S, Thibaudeau L, Gregory LS, Hutmacher DW, Clements JA (2014) A humanized tissue-engineered in vivo model to dissect interactions between human prostate cancer cells and human bone. Clin Exp Metastasis. doi: 10.1007/s10585-014-9638-5

4. Caley MP, Kogianni G, Adamarek A, Gronau JH, Rodriguez-Teja M, Fonseca AV, Mauri F, Sandison A, Rhim JS, Palmieri C, Cobb JP, Waxman J, Sturge J (2012) TGFbeta1-Endo180-dependent collagen deposition is dysregulated at the tumour–stromal interface in bone metastasis. J Pathol 226(5):775–783. doi: 10.1002/path.3958

5. Berning M, Pratzel-Wunder S, Bickenbach JR, Boukamp P (2015) Three-dimensional in vitro skin and skin cancer models based on human fibroblast-derived matrix. Tissue Eng Part C Methods. doi: 10.1089/ten.TEC.2014.0698

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