Trehalose-induced SIRT1/AMPK activation regulates SREBP-1c/PPAR-α to alleviate lipid accumulation in aged liver
Author:
Funder
Kerman University of Medical Sciences
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology,General Medicine
Link
https://link.springer.com/content/pdf/10.1007/s00210-023-02644-w.pdf
Reference42 articles.
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2. Arai C, Arai N, Mizote A, Kohno K, Iwaki K, Hanaya T, Arai S, Ushio S, Fukuda S (2010) Trehalose prevents adipocyte hypertrophy and mitigates insulin resistance. Nutr Res 30(12):840–848
3. Attal N, Marrero E, Thompson KJ, McKillop IH (2022) Role of AMPK-SREBP signaling in regulating fatty acid binding-4 (FABP4) expression following ethanol metabolism. Biology 11(11):1613
4. Bahri F, Khaksari M, Movahedinia S, Shafiei B, Rajizadeh MA, Nazari-Robati M (2021) Improving SIRT1 by trehalose supplementation reduces oxidative stress, inflammation, and histopathological scores in the kidney of aged rats. J Food Biochem 45(10):e13931
5. Bárcena B, Salamanca A, Pintado C, Mazuecos L, Villar M, Moltó E, Bonzón-Kulichenko E, Vázquez J, Andrés A, Gallardo N (2021) Aging induces hepatic oxidative stress and nuclear proteomic remodeling in liver from Wistar rats. Antioxidants 10(10):1535
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