Carvedilol attenuates inflammatory reactions of lipopolysaccharide-stimulated BV2 cells and modulates M1/M2 polarization of microglia via regulating NLRP3, Notch, and PPAR-γ signaling pathways
Author:
Funder
Ardabil University of Medical Sciences
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology,General Medicine
Link
https://link.springer.com/content/pdf/10.1007/s00210-023-02914-7.pdf
Reference52 articles.
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2. Amirshahrokhi K, Niapour A (2022) Carvedilol attenuates brain damage in mice with hepatic encephalopathy. Int Immunopharmacol 111:109119
3. Bao Y, Zhu Y, He G, Ni H, Liu C, Ma L, Zhang L, Shi D (2019) Dexmedetomidine attenuates neuroinflammation in LPS-stimulated BV2 microglia cells through upregulation of miR-340. Drug Des Dev Ther 13:3465–3475
4. Becher B, Spath S, Goverman J (2017) Cytokine networks in neuroinflammation. Nat Rev Immunol 17:49–59
5. Cacci E, Ajmone-Cat MA, Anelli T, Biagioni S, Minghetti L (2008) In vitro neuronal and glial differentiation from embryonic or adult neural precursor cells are differently affected by chronic or acute activation of microglia. Glia 56:412–425
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