Hydrolysis of the non-canonical cyclic nucleotide cUMP by PDE9A: kinetics and binding mode
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology,General Medicine
Link
http://link.springer.com/article/10.1007/s00210-018-1582-5/fulltext.html
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2. Beckert U, Wolter S, Hartwig C, Bähre H, Kaever V, Ladant D, Frank DW, Seifert R (2014b) ExoY from Pseudomonas aeruginosa is a nucleotidyl cyclase with preference for cGMP and cUMP formation. Biochem Biophys Res Commun 450:870–874
3. Bellamy TC, Garthwaite J (2001) “cAMP-specific” phosphodiesterase contributes to cGMP degradation in cerebellar cells exposed to nitric oxide. Mol Pharmacol 59:54–61
4. Bender AT, Beavo JA (2006) Cyclic nucleotide phosphodiesterases: molecular regulation to clinical use. Pharmacol Rev 58:488–520
5. Berrisch S, Ostermeyer J, Kaever V, Kälble S, Hilfiker-Kleiner D, Seifert R, Schneider EH (2017) cUMP hydrolysis by PDE3A. Naunyn Schmiedeberg’s Arch Pharmacol 390:269–280
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