Discovery pharmaceutics—Challenges and opportunities

Author:

Chen Xue-Qing,Antman Melissa D.,Gesenberg Christoph,Gudmundsson Olafur S.

Publisher

Springer Science and Business Media LLC

Subject

Pharmaceutical Science

Reference33 articles.

1. Florence AT, Attwood D.Physicochemical Principles of Pharmacy: London, UK: Macmillan Press, 1998.

2. Gudmundsson OS, Venkatesh S. Strategies for in silico and experimental screening of physicochemical properties. In: Borchardt RT, Kerns EH, Lipinski CA, Thakker DR, Wang B, eds.Pharmaceutical Profiling in Drug Discovery for Lead Selection. Arlington, VA: AAPS Press; 2004;393–412.

3. Kerns E. High throughput physicochemical profiling for drug discovery.J Pharm Sci. 2001;90:1838–1858.

4. Di L, Kerns EH. Profiling drug-like properties in discovery research.Curr Opin Chem Biol. 2003;7:402–408.

5. Hageman MJ. Solubility, solubilization, and dissolution in drug delivery during lead optimization. AAPS Workshop, on Optimization of Drug-Like Properties During Lead Optimization; September 19–22, 2004; Parsippany, NJ.

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