Abstract
Abstract
Purpose
The aim of this study was to clarify the most essential analytical features of N-(adamantan-1-yl)-1-(cyclohexylmethyl)-1H-indazole-3-carboxamide (one of the newest cannabimimetics called ACHMINACA), to make them useful for analytical identification of this compound.
Methods
The compound was analyzed by gas chromatography–mass spectrometry, high-resolution liquid chromatography–mass spectrometry, crystal X-ray diffraction and spectroscopic methods such as nuclear magnetic resonance, Raman, and infrared spectroscopies.
Results
Detailed and comprehensive analytical data have been acquired for ACHMINACA.
Conclusions
Although brief descriptions of the partial data of ACHMINACA have appeared recently, this article provides the most detailed and comprehensive analytical data of ACHMINACA to our knowledge. Our data will significantly broaden the knowledge about the compound structure extending the possibility of its orthogonal analysis. The gathered data are useful for forensic, toxicological, and clinical purposes.
Publisher
Springer Science and Business Media LLC
Subject
Biochemistry, medical,Toxicology,Pathology and Forensic Medicine
Reference22 articles.
1. EMCDDA (2019) EU drug markets report 2019. EMCDDA. Europol Luxemburg. https://doi.org/10.2810/561192(open access article)
2. UNODC (2020) World drug report 2020 booklet 4 — Cross-cutting issues: evolving trends and new challenges. https://wdr.unodc.org/wdr2020/field/WDR20_BOOKLET_4.pdf(open access article)
3. Lindigkeit R, Boehme A, Eiserloh I, Luebbecke M, Wiggermann M, Ernst L, Beuerle T (2009) Spice: a never ending story? Forensic Sci Int 191:58–63. https://doi.org/10.1016/j.forsciint.2009.06.008
4. Wiley JL, Marusich JA, Huffman JW (2013) Moving around the molecule: relationship between chemical structure and in vivo activity of synthetic cannabinoids. Life Sci 97:55–63. https://doi.org/10.1016/j.lfs.2013.09.011
5. Choi H, Heo S, Kim E, Hwang BY, Lee C, Lee J (2013) Identification of (1-pentylindol-3-yl)-(2,2,3,3-tetramethylcyclopropyl)methanone and its 5-pentyl fluorinated analog in herbal incense seized for drug trafficking. Forensic Toxicol 31:86–92. https://doi.org/10.1007/s11419-012-0170-5
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