Author:
Raffaele A.,Ferlini C. M.,Fusi G.,Lenti M. V.,Cereda E.,Caimmi S. M. E.,Bertozzi M.,Riccipetitoni G.
Abstract
Abstract
Purpose
A multidisciplinary approach to Inflammatory Bowel Disease (IBD) has recently demonstrated a positive impact in pediatric patients, reducing dropout rates and facilitating the transition to adult care. Our study aims to evaluate how this approach influences disease activity, dropout rates, and transition.
Methods
We conducted a longitudinal observational study including all patients diagnosed with IBD during pediatric-adolescent age, with a minimum follow-up period of 12 months. For each patient, endpoints included therapeutic approach, need for surgery and transition features.
Results
We included 19 patients: 13 with Ulcerative Colitis (UC) and 6 with Crohn’s disease (CD). Most patients required multiple lines of therapy, with over 50% in both groups receiving biological drugs. Compliance was good, with a single dropout in each group (10, 5%). The need for surgery was significantly higher in the CD group compared to the UC group (16% vs. 7.7%, p < 0.01). Mean age at transition was significantly higher in the UC group compared to the CD group (19.2 ± 0.7 years SD vs. 18.3 ± 0.6 years SD, p < 0.05).
Conclusions
In our experience, the multidisciplinary approach to IBD in transition-age patients appears effective in achieving clinical remission, offering the potential to reduce therapeutic dropouts.
Funder
Università degli Studi di Pavia
Publisher
Springer Science and Business Media LLC