Severe proteinuria (but not being on dialysis) may be associated with initial inadequate complement inhibition and delayed hematological response to eculizumab therapy
Author:
Publisher
Springer Science and Business Media LLC
Subject
Nephrology
Link
https://link.springer.com/content/pdf/10.1007/s40620-023-01831-5.pdf
Reference6 articles.
1. Bayer G, von Tokarski F, Thoreau B et al (2019) Etiology and outcomes of thrombotic microangiopathies. Clin J Am Soc Nephrol 14:557–566
2. Fakhouri F, Zuber J, Frémeaux-Bacchi V, Loirat C (2017) Haemolytic uraemic syndrome. Lancet 390:681–696
3. Cavero T, Rabasco C, López A et al (2017) Eculizumab in secondary atypical haemolytic uraemic syndrome. Nephrol Dial Transplant 32:466–474
4. Bouwmeester RN, Ter Avest M, Wijnsma KL et al (2020) Case report: variable pharmacokinetic profile of eculizumab in an aHUS patient. Front Immunol 11:612706
5. Lee J, Imani P, Geer J et al (2015) The pharmacokinetics of intradialytic administration of eculizumab in an infant. Am J Kidney Dis 66:1105–1106
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