Author:
Bruins Susanne,van Bergen Elsje,Masselink Maurits W.,Barzeva Stefania A.,Hartman Catharina A.,Otten Roy,Rommelse Nanda N. J.,Dolan Conor V.,Boomsma Dorret I.
Abstract
AbstractThere is a negative association between intelligence and psychopathology. We analyzed data on intelligence and psychopathology to assess this association in seven-year-old Dutch twin pairs (ranging from 616 to 14,150 depending on the phenotype) and estimated the degree to which genetic and environmental factors common to intelligence and psychopathology explain the association. Secondly, we examined whether genetic and environmental effects on psychopathology are moderated by intelligence. We found that intelligence, as assessed by psychometric IQ tests, correlated negatively with childhood psychopathology, as assessed by the DSM-oriented scales of the Child Behavior Check List (CBCL). The correlations ranged between − .09 and − .15 and were mainly explained by common genetic factors. Intelligence moderated genetic and environmental effects on anxiety and negative affect, but not those on ADHD, ODD, and autism. The heritability of anxiety and negative affect was greatest in individuals with below-average intelligence. We discuss mechanisms through which this effect could arise, and we end with some recommendations for future research.
Funder
ZonMw
Nederlandse Organisatie voor Wetenschappelijk Onderzoek
Koninklijke Nederlandse Akademie van Wetenschappen
Publisher
Springer Science and Business Media LLC
Reference57 articles.
1. Achenbach TM (1999) The Child Behavior Checklist and related instruments. In: The use of psychological testing for treatment planning and outcomes assessment, 2nd ed. Lawrence Erlbaum Associates Publishers, Mahwah, NJ, US, pp 429–466
2. Achenbach TM, Dumenci L, Rescorla LA (2003) DSM-oriented and empirically based approaches to constructing scales from the same item pools. J Clin Child Adolesc Psychol 32:328–340. https://doi.org/10.1207/S15374424JCCP3203_02
3. American Psychiatric Association (1994) DSM-4.: diagnostic and statistical manual of mental disorders, 4. ed. American psychiatric Association, Washington
4. American Psychiatric Association AP (2013) DSM 5 Diagnostic and statistical manual of mental disorders. DSM 5 Diagnostic and statistical manual of mental disorders. P. 94
5. Bartels M, BeijsterveldtVan CEM, Derks EM et al (2007) Young Netherlands twin register (Y-NTR): a longitudinal multiple Informant study of problem behavior. Twin Res Human Gene 10:3–11. https://doi.org/10.1375/twin.10.1.3