Reactive oxygen species-mediated activation of the Akt/ASK1/p38 signaling cascade and p21Cip1 downregulation are required for shikonin-induced apoptosis-Reference-Cited by-同舟云学术

Reactive oxygen species-mediated activation of the Akt/ASK1/p38 signaling cascade and p21Cip1 downregulation are required for shikonin-induced apoptosis

Published:2013-04-02 Issue:7 Volume:18 Page:870-881
ISSN:1360-8185
Container-title:Apoptosis
language:en
Short-container-title:Apoptosis

Author:

Ahn Jiwon,Won Misun,Choi Jeong-Hae,Kim Yong Sung,Jung Cho-Rock,Im Dong-Su,Kyun Mi-Lang,Lee Kyeong,Song Kyung-Bin,Chung Kyung-Sook

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Biochemistry (medical),Cell Biology,Clinical Biochemistry,Pharmaceutical Science,Pharmacology

Link

http://link.springer.com/content/pdf/10.1007/s10495-013-0835-5.pdf

Reference49 articles.

1. Meng TC, Fukada T, Tonks NK (2002) Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo. Mol Cell 9:387–399

2. Huang C, Li J, Ding M, Leonard SS, Wang L, Castranova V et al (2001) UV induces phosphorylation of protein kinase B (Akt) at Ser-473 and Thr-308 in mouse epidermal Cl 41 cells through hydrogen peroxide. J Biol Chem 276:40234–40240

3. Wang X, McCullough KD, Franke TF, Holbrook NJ (2000) Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival. J Biol Chem 275:14624–14631

4. Kim AH, Khursigara G, Sun X, Franke TF, Chao MV (2001) Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1. Mol Cell Biol 21:893–901

5. Gotoh Y, Cooper JA (1998) Reactive oxygen species- and dimerization-induced activation of apoptosis signal-regulating kinase 1 in tumor necrosis factor-alpha signal transduction. J Biol Chem 273:17477–17482

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