In vitro and in vivo antineoplastic and immunological effects of pterocarpanquinone LQB-118-Reference-Cited by-同舟云学术

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In vitro and in vivo antineoplastic and immunological effects of pterocarpanquinone LQB-118

Published:2016-05-18 Issue:5 Volume:34 Page:541-551
ISSN:0167-6997
Container-title:Investigational New Drugs
language:en
Short-container-title:Invest New Drugs

Author:

Salustiano Eduardo J.,Dumas Matheus L.,Silva-Santos Gabriel G.,Netto Chaquip D.,Costa Paulo R. R.,Rumjanek Vivian M.

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Financiadora de Estudos e Projetos

Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro

Fundação Ary Frauzino para Pesquisa e Controle do Câncer

Instituto Nacional de Ciência e Tecnologia para o Controle do Câncer

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,Oncology

Link

http://link.springer.com/content/pdf/10.1007/s10637-016-0359-2.pdf

Reference39 articles.

1. Donnelly DMX, Boland GM (1995) Isoflavonoids and neoflavonoids: naturally occurring O-heterocycles. Nat Prod Rep 12:321. doi: 10.1039/np9951200321

2. Kostelac D, Rechkemmer G, Briviba K (2003) Phytoestrogens modulate binding response of estrogen receptors alpha and beta to the estrogen response element. J Agric Food Chem 51:7632–7635. doi: 10.1021/jf034427b

3. Zhou H, Lutterodt H, Cheng Z, Yu LL (2009) Anti-inflammatory and antiproliferative activities of trifolirhizin, a flavonoid from Sophora flavescens roots. J Agric Food Chem 57:4580–4585. doi: 10.1021/jf900340b

4. da Silva AJ, Netto CD, Costa PR (2004) The first synthesis of (±)-3, 4-dihydroxy-8,9-methylenedioxypterocarpan, an antitumoral agent and its coumestan derivative. J Braz Chem Soc 15:979–981. doi: 10.1590/S0103-50532004000600029

5. Netto CD, Santos ES, Castro CP, da Silva AJ, Rumjanek VM, Costa PR (2009) (+/−)-3,4-dihydroxy-8,9-methylenedioxypterocarpan and derivatives: cytotoxic effect on human leukemia cell lines. Eur J Med Chem 44:920–925. doi: 10.1016/j.ejmech.2008.01.027

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2. Flavonoids as Inspiration for the Design and Synthesis of New Antiproliferative, Antiparasitic and Antiviral Compounds: An Account;Journal of the Brazilian Chemical Society;2024

3. LQB-118 Suppresses Migration and Invasion of Prostate Cancer Cells by Modulating the Akt/GSK3β Pathway and MMP-9/Reck Gene Expression;Anticancer Research;2022-12-30

4. Design, synthesis, and antitumor evaluation of novel anthraquinone derivatives;Medicinal Chemistry Research;2020-06-18

5. The pterocarpanquinone LQB 118 inhibits inflammation triggered by zymosan in vivo and in vitro;International Immunopharmacology;2020-06

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