Abstract
AbstractLinking derivation of potential target values of PCDD/Fs in animal feed with risk assessment for consumer protection is a challenge when tolerable weekly intake (TWI) and transfer factors from feed to food are considered. Generally, maximum values for feed and food are set separately without considering the feed and the food producing animal as an important factor along the food chain from farm to fork. Levels of contaminants in feed can accumulate in animals and their products effect consumers at the end of the food chain. Hence, the process of setting legal maximum levels of contaminants should account for transfer from feed consumed by food producing animals into animal products for human consumption. Here, we calculated potential target values of PCDD/F in feed to ensure that animal products such as milk from dairy cows, eggs from laying hens and pork and pork products from fattening pigs are safe for human consumption. In our approach, we calculated potential target values of PCDD/Fs in animal feed using transfer factors for PCDD/F-TEQs from feed to milk fat, eggs fat, and fat in pork and pork products, taking into account the tolerable weekly intake derived by European Food Safety Authority. We assumed equal proportions of WHO-PCDD/F-TEQ and WHO-PCB-TEQ in feed. Potential target values of PCDD/F in feed are expressed as the quantity of toxicologically evaluated PCDD/Fs, expressed in WHO toxic equivalents (WHO2005-PCDD/F-TEQ) per kg feed with 12% moisture. In the current approach, derived values would be 10–54 times lower than the current legal maximum level of 0.75 ng WHO2005-PCDD/F-TEQ per kg feed (12% moisture), according to Directive 2002/32/EC as amended.
Funder
Bundesinstitut für Risikobewertung (BfR)
Publisher
Springer Science and Business Media LLC
Subject
Agronomy and Crop Science,Food Animals,Food Science,Biotechnology
Reference41 articles.
1. Amutova F, Delannoy M, Baubekova A, Konuspayeva G, Jurijanz S (2021) Transfer of persistent organic pollutants in food of animal origin—meta-analysis of published data. Chemosphere 262:128351. https://doi.org/10.1016/j.chemosphere.2020.128351
2. Brambilla G, Fochi I, Falce M, De Filippis SP, Ubaldi A, di Domenico A (2008) PCDD and PCDF depletion in milk from dairy cows according to the herd metabolic scenario. Chemosphere 73:S216–S219
3. Commission Regulation (EC) No 1881/2006 of 19 December 2006 setting maximum levels for certain contaminants in foodstuffs. OJ L 364, 20.12.2006, p. 5–24 (as amended)
4. Commission Regulation (EU) No 1259/2011 of 2 December 2011 amending Regulation (EC) No 1881/2006 as regards maximum levels for dioxins, dioxin-like PCBs and non dioxin-like PCBs in foodstuffs. OJ L 320, 3.12.2011, p. 18–23
5. Commission Regulation (EU) No 277/2012 of 28 March 2012 amending Annexes I and II to Directive 2002/32/EC of the European Parliament and of the Council as regards maximum levels and action thresholds for dioxins and polychlorinated biphenyls. OJ L 91, p. 1–17
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