Investigation of [3H]diazepam derivatives as allosteric modulators of GABAA receptor α1β2γ2 subtypes: combination of molecular docking/dynamic simulations, pharmacokinetics/drug-likeness prediction, and QSAR analysis
Author:
Publisher
Springer Science and Business Media LLC
Subject
Physical and Theoretical Chemistry,Condensed Matter Physics
Link
https://link.springer.com/content/pdf/10.1007/s11224-022-02029-4.pdf
Reference66 articles.
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3. Sigel E, Steinmann ME (2012) Structure, function, and modulation of GABAA receptors. J Biol Chem 287:40224–40231. https://doi.org/10.1074/jbc.R112.386664
4. Miller PS, Aricescu AR (2014) Crystal structure of a human GABAA receptor. Nature 512:270–275. https://doi.org/10.1038/nature13293
5. Olsen RW, Sieghart W (2008) International Union of Pharmacology. LXX. Subtypes of γ-aminobutyric acidA receptors: classification on the basis of subunit composition, pharmacology, and function. Update Pharmacol Rev 60:243–260. https://doi.org/10.1124/pr.108.00505
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