Predicting Intestinal Precipitation—A Case Example for a Basic BCS Class II Drug-Reference-Cited by-同舟云学术

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Predicting Intestinal Precipitation—A Case Example for a Basic BCS Class II Drug

Published:2010-08-18 Issue:10 Volume:27 Page:2119-2130
ISSN:0724-8741
Container-title:Pharmaceutical Research
language:en
Short-container-title:Pharm Res

Author:

Carlert Sara,Pålsson Anna,Hanisch Gunilla,von Corswant Christian,Nilsson Catarina,Lindfors Lennart,Lennernäs Hans,Abrahamsson Bertil

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Organic Chemistry,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biotechnology

Link

http://link.springer.com/content/pdf/10.1007/s11095-010-0213-8.pdf

Reference30 articles.

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2. Dai WG, Dong LC, Shi X, Nguyen J, Evans J, Xu Y, et al. Evaluation of drug precipitation of solubility-enhancing liquid formulations using milligram quantities of a new molecular entity (NME). J Pharm Sci. 2007;96:2957–69.

3. Carino SR, Sperry DC, Hawley M. Relative bioavailability estimation of carbamazepine crystal forms using an artificial stomach-duodenum model. J Pharm Sci. 2006;95:116–25.

4. Kostewicz ES, Wunderlich M, Brauns U, Becker R, Bock T, Dressman JB. Predicting the precipitation of poorly soluble weak bases upon entry in the small intestine. J Pharm Pharmacol. 2004;56:43–51.

5. Kobayashi M, Sada N, Sugawara M, Iseki K, Miyazaki K. Development of a new system for prediction of drug absorption that takes into account drug dissolution and pH change in the gastro-intestinal tract. Int J Pharm. 2001;221:87–94.

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