Application of Pharmacokinetic Modeling to Characterize Hepatobiliary Disposition of Imaging Agents and Alterations due to Liver Injury in Isolated Perfused Rat Livers-Reference-Cited by-同舟云学术

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Application of Pharmacokinetic Modeling to Characterize Hepatobiliary Disposition of Imaging Agents and Alterations due to Liver Injury in Isolated Perfused Rat Livers

Published:2023-06-22 Issue:11 Volume:40 Page:2513-2523
ISSN:0724-8741
Container-title:Pharmaceutical Research
language:en
Short-container-title:Pharm Res

Author:

Jeong Angela^ORCID,Pastor Catherine M.,Brouwer Kim L. R.^ORCID

Funder

National Institute of General Medical Sciences

Swiss National Science Foundation

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Organic Chemistry,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biotechnology

Link

https://link.springer.com/content/pdf/10.1007/s11095-023-03549-2.pdf

Reference39 articles.

1. Pastor CM, Mullhaupt B, Stieger B. The role of organic anion transporters in diagnosing liver diseases by magnetic resonance imaging. Drug Metab Dispos. 2014;42:675–84.

2. Kusuhara H. Imaging in the study of membrane transporters. Clin Pharmacol Ther. 2013;94:33–6.

3. Guo Y, Chu X, Parrott NJ, Brouwer KLR, Hsu V, Nagar S, et al. Advancing predictions of tissue and intracellular drug concentrations using in vitro, imaging and PBPK modeling approaches. Clin Pharmacol Ther. 2018;104:865–89.

4. Hoekstra LT, de Graaf W, Nibourg GA, Heger M, Bennink RJ, Stieger B, et al. Physiological and biochemical basis of clinical liver function tests. Ann Surg. 2013;257:27–36.

5. Giacomini, KM, Huang S, Tweedie DJ, et al. (The International Transporter Consortium). Membrane transporters in drug development. Nat Rev Drug Discov. 2010;9(3):215–36.

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