Investigation of the Pharmacokinetics of Romiplostim in Rodents with a Focus on the Clearance Mechanism

Author:

Wang Yow-Ming C.,Sloey Bethlyn,Wong Teresa,Khandelwal Prerna,Melara Rebeca,Sun Yu-Nien

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Organic Chemistry,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biotechnology

Reference20 articles.

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2. Brown AS EJ, Martin JF. Megakaryocytopoiesis: the megakaryocyte/platelet haemostatic axis. In: Franz von Bruchhausen UW, editor. Platelets and Their Factors: Springer; 1 edition (July 15, 1997) 1997. p. 3–26.

3. Jackson C, Arnold JT, Pestina TI, Stenberg PE. Megakaryocyte Biology. In: Kuter DJ, Hunt P, Sheridan W, Zucker-Franklin D, editors. Thromobopoiesis and Thrombopoietins; Molecular, Cellular, Preclinical, and Clinical Biology. Totowa, New Jersey.: Humana Press; 1997. p. 3–40.

4. Hall MP, Gegg C, Walker K, Spahr C, Ortiz R, Patel V, et al. Ligand-Binding Mass Spectrometry to Study Biotransformation of Fusion Protein Drugs and Guide Immunoassay Development: Strategic Approach and Application to Peptibodies Targeting the Thrombopoietin Receptor. AAPS J.

5. Molineux G, Newland A. Development of romiplostim for the treatment of patients with chronic immune thrombocytopenia: from bench to bedside. Br J Haematol. 2010;150:9–20.

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