Design, synthesis and assay of 2-(4-phenylpiperazin-1-yl)pyrimidine-5- carboxamide derivatives as acetylcholinesterase inhibitors
Author:
Publisher
Springer Science and Business Media LLC
Subject
Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics
Link
https://link.springer.com/content/pdf/10.1007/s00044-022-02949-0.pdf
Reference24 articles.
1. Blennow K, de Leon MJ, Zetterberg H. Alzheimer’s disease. Lancet. 2006;368:387–403. https://doi.org/10.1016/S0140-6736(06)69113-7.
2. 2021 Alzheimer’s disease facts and figures, Alzheimers Dement. 2021;17:327−406. https://doi.org/10.1002/alz.12328.
3. Huang Y, Mucke L. Alzheimer mechanisms and therapeutic strategies. Cell. 2012;148:1204–22. https://doi.org/10.1016/j.cell.2012.02.040.
4. Knopman DS, Amieva H, Petersen RC, Chetelat G, Holtzman DM, Hyman BT, et al. Alzheimer disease. Nat Rev Dis Prim. 2021;7:33. https://doi.org/10.1038/s41572-021-00269-y.
5. Wang K, Shi J, Zhou Y, He Y, Mi J, Yang J, et al. Design, synthesis and evaluation of cinnamic acid hybrids as multi-target-directed agents for the treatment of Alzheimer’s disease. Bioorg Chem. 2021;112:104879. https://doi.org/10.1016/j.bioorg.2021.104879.
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