Synthesis, in vitro cytotoxicity and anti-platelet activity of new 1,3-bentzenedisulfonamides

Author:

Xiu-jie Liu,Zhi-hao Zhang,Qing-song Deng,Xin Chen,Chao-qing Wang

Publisher

Springer Science and Business Media LLC

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics

Reference17 articles.

1. Born GVR (1962) Aggregation of blood platelets by adenosine diphosphate and its reversal. Nature 194(4832):927–929

2. Deng QS, Zhang QX, Wang CQ, Liu XJ (2017) Synthesis and in vitro activity on anti-platelet aggregation of N 1 , N 3-benzhydryl-4-methoxy-1,3-benzenedisulfonam-idederivatives. Chin J Med Chem 22(5):355–359+366

3. Fontenele JB, Leal LK, Silveira ER, Felix FH, Bezerra Felipe CF, Viana GS (2009) Anti-platelet effects of piplartine, analkamide isolated from Piper tuberculatum: possible involvement of cyclooxygenase blockade and antioxidant activity. J Pharm Pharmacol 61(4):511–515

4. Giridhar R, Tamboli RS, Ramajayam R, Prajapati DG, Yadav MR (2012) Assessment of anti-platelet activity of 2-aminopyrimidines. Cheminform 50(33):428–432

5. Li GA, Wang X, Meng X, Lin YB, Li X, Liu XJ (2015) Design, synthesis of novel N, N'- bis-(halogenophenyl)-4-methoxybenzene-1,3-disulfonamides and evaluation of their anti- platelet aggregation activity. Acta Pharm Sin 50(2):185–190

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