Lipid nanoparticles-encapsulated brain-derived neurotrophic factor mRNA delivered through the round window niche in the cochleae of guinea pigs
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Neuroscience
Link
http://link.springer.com/content/pdf/10.1007/s00221-020-05970-0.pdf
Reference23 articles.
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2. Crowley ST, Fukushima Y, Uchida S et al (2019) Enhancement of motor function recovery after spinal cord injury in mice by delivery of brain-derived neurotrophic factor mRNA. Mol Ther Nucleic Acids 17:465–476. https://doi.org/10.1016/j.omtn.2019.06.016
3. Guan S, Rosenecker J (2017) Nanotechnologies in delivery of mRNA therapeutics using nonviral vector-based delivery systems. Gene Ther 24:133–143
4. Leake PA, Stakhovskaya O, Hetherington A et al (2013) Effects of brain-derived neurotrophic factor (BDNF) and electrical stimulation on survival and function of cochlear spiral ganglion neurons in deafened, developing cats. JARO J Assoc Res Otolaryngol 14:187–211. https://doi.org/10.1007/s10162-013-0372-5
5. Leake PA, Akil O, Lang H (2020) Neurotrophin gene therapy to promote survival of spiral ganglion neurons after deafness. Hear Res 394(1):107955. https://doi.org/10.1016/j.heares.2020.107955
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