Phase I study of recombinant human tumor necrosis factor

Author:

Kimura Kiyoji,Taguchi Tetsuo,Urushizaki Ichiro,Ohno Ryuzo,Abe Osahiko,Furue Hisashi,Hattori Takao,Ichihashi Hidehito,Inoguchi Kiyoshi,Majima Hisashi,Niitani Hisanobu,Ota Kazuo,Saito Tatsuo,Suga Shoji,Suzuoki Yozo,Wakui Akira,Yamada Kazumasa,

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Cancer Research,Pharmacology,Toxicology,Oncology

Reference31 articles.

1. Beutler B, Greenwald D, Hulmes JD, Chang M, Pan YCE, Mathison J, Cerami A (1985a) Identity of tumour necrosis factor and the macrophage-secreted factor cachectin. Nature 316: 552?554

2. Beutler B, Millsark IW, Cerami AC (1985b) Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin. Science 229: 869?871

3. Blick MB, Sherwin SA, Rosenblum MG, Gutterman JU (1986) A phase I trial of recombinant tumor necrosis factor (rTNF) in cancer patients. Proc Soc Clin Oncol 5: 14

4. Carswell EA, Old LJ, Kassel RL, Green S, Fiore N (1975) An endotoxin-induced serum factor that causes necrosis of tumors. Proc Natl Acad Sci USA 72: 3666?3670

5. Chapman PB, Lester TJ, Casper ES, Gabrilove JL, Kempin S, Welt S, Sherwin S, Old LJ, Oettgen HF (1986) Phase I study of recombinant tumor necrosis factor (rTNF). Proc Am Soc Clin Oncol 5: 231

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