1. For reviews on the 1,3,5-thiadiazine chemistry, see: a) Smalley RK (1996) 1,3,5-Oxadiazines and 1,3,5-Thiadiazines. In: Boulton AJ (ed) Comprehensive Heterocyclic Chemistry II, Vol. 6. Elsevier, Oxford, UK, p 783; b) Moody CJ (1984) Polyoxa, Polythia and Polyaza Six-Membered Ring Systems. In: Katritzky AR, Rees CW (eds) Comprehensive Heterocyclic Chemistry, Vol. 3. Pergamon, Oxford, UK, p 1039
2. a) Nakaya M, Fukushi Y, Shiraishi S, Nakamura M, Numata S, Kodaka K, Ooka M (1989) Pat EP 308961; (1989) Chem Abstr 111:174137a; b) Nihon Nohuyaku Co Ltd (1980) Pat Jpn 8053206; (1980) Chem Abstr 93:90206u
3. Synthesis and in vitro antimicrobial activity of 6-substituted 2H-1,3,5-thiadiazine-2,4(3H)-diones
4. For instance, see: a) Chen G, Zou J, Song X, Li Y (1996) Yaoxue Xuebao 31:425; (1997) Chem Abstr 126:29036x; b) Ilhan E, Capan G, Ergenc N, Uzun M, Kiraz M, Kaya B (1995) Farmaco 50(11):787; c) Ertan M, Bilgil AA, Palaska E, Yulug N (1992) Arzneim-Forsch (Drug Research) 42:160; d) Hussein MA, El-Shorbagi AN, Khallil AR (2001) Arch Pharm 334(10):305; e) Ertan M, Tayhan AB, Yulug N (1990) Arch Pharm 323(9):605; f) Saraç S, Ertan M, Balkan A, Yulug N (1991) Arch Pharm 324(7):449; g) El-Shorbagi AN (2000) Arch Pharm 333(9):281; h) Aboul-Fadl T, Hussein MA, El-Shorbagi AN, Khallil AR (2002) Arch Pharm 335(9):438
5. For instance, see: a) Chupp JP (1971) US Pat 3741964; (1973) Chem Abstr 79:78857k; b) Vicentini CB, Mares D, Tartari A, Manfrini M, Forlani G (2004) J Agr Food Chem 52:1898; c) Vicentini CB, Guccione S, Giurato L, Ciaccio R, Mares D, Forlani G (2005) J Agr Food Chem 53:3848