Abstract
AbstractCongenital abdominal wall defects, namely, gastroschisis and omphalocele, are rare congenital malformations with significant morbidity. The long-term burden of these anomalies to families and health care providers has not previously been assessed. We aimed to determine the need for hospital admissions and the requirement for surgery after initial admission at birth. For our analyses, we identified all infants with either gastroschisis (n=178) or omphalocele (n=150) born between Jan 1, 1998, and Dec 31, 2014, in the Register of Congenital Malformations. The data on all hospital admissions and operations performed were acquired from the Finnish Hospital Discharge Register between Jan 1, 1998, and Dec 31, 2015, and compared to data on the whole Finnish pediatric population (0.9 million) live born 1993−2008. Patients with gastroschisis and particularly those with omphalocele required hospital admissions 1.8 to 5.7 times more than the general pediatric population (p<0.0001). Surgical interventions were more common among omphalocele than gastroschisis patients (p=0.013). At the mean follow-up of 8.9 (range 1.0–18.0) years, 29% (51/178) of gastroschisis and 30% (45/150) of omphalocele patients required further abdominal surgery after discharge from the neonatal admission.Conclusion: Patients with gastroschisis and especially those with omphalocele, are significantly more likely than the general pediatric population to require hospital care. Nevertheless, almost half of the patients can be treated without further surgery, and redo abdominal surgery is only required in a third of these children.
What is Known:• Gastroschisis and omphalocele are congenital malformations with significant morbidity• There are no reports on the long-term need for hospital admissions and surgery in these childrenWhat is New:• Patients with abdominal wall defects are significantly more likely than the general pediatric population to require hospital care• Almost half of the patients can be treated without further surgery, and abdominal redo operations are only required in a third of these children
Funder
Clinical Research Institute HUCH
Lastentautien Tutkimussäätiö
Emil Aaltosen Säätiö
Publisher
Springer Science and Business Media LLC
Subject
Pediatrics, Perinatology, and Child Health
Cited by
3 articles.
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