Pharmacokinetics of tramadol is affected by MDR1 polymorphism C3435T-Reference-Cited by-同舟云学术

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Pharmacokinetics of tramadol is affected by MDR1 polymorphism C3435T

Published:2007-01-30 Issue:4 Volume:63 Page:419-421
ISSN:0031-6970
Container-title:European Journal of Clinical Pharmacology
language:en
Short-container-title:Eur J Clin Pharmacol

Author:

Slanař Ondřej,Nobilis Milan,Kvétina Jaroslav,Matoušková Olga,Idle Jeffrey R.,Perlík František

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Link

http://link.springer.com/content/pdf/10.1007/s00228-006-0255-3.pdf

Reference6 articles.

1. Pedersen RS, Damkier P, Brosen K (2006) Enantioselective pharmacokinetics of tramadol in CYP2D6 extensive and poor metabolizers. Eur J Clin Pharmacol 62:513–521

2. Wang G, Zhang H, He F, Fang X (2006) Effect of the CYP2D6*10 C188T polymorphism on postoperative tramadol analgesia in a Chinese population. Eur J Clin Pharmacol 62:927–931

3. Wu WN, McKown LA, Liao S (2002) Metabolism of the analgesic drug ULTRAM (tramadol hydrochloride) in humans: API-MS and MS/MS characterization of metabolites. Xenobiotica 32:411–425

4. Poulsen L, Arendt-Nielsen L, Brosen K, Sindrup SH (1996) The hypoalgesic effect of tramadol in relation to CYP2D6. Clin Pharmacol Ther 60:636–644

5. Gleason PP, Frye RF, O’Toole T (1997) Debilitating reaction following the initial dose of tramadol. Ann Pharmacother 31:1150–1152

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