Artificial Triterpenoid Fatty Acid Ester Isolated From the Leaves of Phytolacca icosandra L

Author:

Galarraga ElierORCID,Mavares Andersson,Urdaneta Neudo,Rodríguez-Lugo Rafael E.,Amaro-Luis Juan Manuel

Abstract

Abstract The methanol extract form the leaves of Phytolacca icosandra L., afforded the unprecedented artificial triterpenoid fatty acid ester 1 derived from the new natural triterpenoid phytolaccagenic acid 3-O-myristate (1a), along with the three known triterpenoids serjanic, acinosolic and phytolaccagenic acid (24). Their structures were stablished by HR-EI-MS, 1D and 2D NMR techniques. The possible mechanistic formation of 1 is proposed, and the in vitro toxicity of all compounds was assessed using the brine shrimp lethality assay (BSLA). Graphic Abstract

Funder

USB-DID

Publisher

Springer Science and Business Media LLC

Subject

Organic Chemistry,Plant Science,Pharmacology,Toxicology,Biochemistry,Food Science,Analytical Chemistry

Reference27 articles.

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