RET/PTC activation in human thyroid carcinomas

Author:

Fusco A.,Santoro M.,Grieco M.,Carlomagno F.,Dathan N.,Fabien N.,Berlingieri M. T.,Li Z.,De Franciscis V.,Salvatore D.,Melillo R. M.,Portella G.,Cerrato A.,Colantuoni V.,Vecchio G.

Publisher

Springer Science and Business Media LLC

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism

Reference9 articles.

1. Fusco A., Grieco M., Santoro M., Berlingieri M.T., Di Fiore P.P., Pilotti S., Pierotti M.A., Deila Porta G., Vecchio G. A new oncogene in human thyroid papillary carcinomas and their lymph-nodal metastases. Nature 328: 170, 1987.

2. Grieco M., Santoro M., Berlingieri M.T., Melillo R.M., Donghi R., Bongarzone I., Pierotti M.A., Delia Porta G., Fusco A., Vecchio G. PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas. Cell 60: 557, 1990.

3. Santoro M., Carlomagno F., Hay I.D., Herrmann M.A., Grieco M., Melillo R., Bongarzone I., Pierotti M.A., Delia Porta G., Berger N., Peix J.L., Paulin C, Fabien N., Vecchio G., Jenkins R.B., Fusco A. RET oncongene activation in human thyroid neoplasms is restricted to the papillary carcinoma subtype. J. Clin. Invest. 89: 1517, 1992.

4. Pierotti M.A., Santoro M., Jenkins R.B., Sozzi G., Bongarzone I., Grieco M., Monzini N., Miozzo M., Herrmann M.A., Fusco A., Hay I.D., Dello Porta G., Vecchio G. Characterization of a chromosome 10q inversion juxtaposing RET and H4 genes and creating the oncogenic sequence PTC. Proc. Natl. Acad. Sci. USA 89: 1616, 1992.

5. Bongarzone I., Monzini N., Borrello M.G., Carcano C, Ferraresi Arighi E., Mondellini P., Delia Porta G., Pierotti M.A. Molecular characterization of a thyroid tumor-specific transforming sequence formed by the fusion of ret tyrosine kinase and the regulatory subunit RI of cyclic AMP protein kinase A. Mol. Cell. Biol. 13: 358, 1993.

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