Problems Associated with Assessment of the Contribution of Individual Forms of Cytochrome P450 to the Metabolism of Xenobiotics

Author:

Philpot Richard M.,Overby Lila

Publisher

Springer Berlin Heidelberg

Reference14 articles.

1. Boyd MR (1980) Biochemical mechanisms in pulmonary toxicity of furan derivatives. Hodgson E, Bend JR, and Philpot RM (eds) Reviews in Biochemical Toxicology 2:71–102, Elsevier North Holland, New York

2. Domin BA and Philpot RM (1986) The effect of substrate on the expression of activity catalyzed by cytochrome P-450. Metabolism mediated by rabbit isozyme 6 in pulmonary microsomal and reconstituted monooxygenase systems. Arch. Biochem. Biophys. 246: 128–142

3. Domin BA, Devereux TR and Philpot RM (1986) The cytochrome P-450 monooxygenase system of rabbit lung: enzyme components, activities, and induction in the nonciliated bronchiolar epithelial ( Clara) cell, alveolar type II cell, and alveolar macrophage. Mol Pharmacol 30: 296–303

4. Estabrook RW, Peterson J, Baron J, and Hildebrandt A (1972) The spectrophotometric measurement of turbid suspensions of cytochromes associated with drug metabolism. Chignell C (ed) Methods of Pharmacology 2:303–350, Appleton-Century-Crofts, New York

5. Gasser R, Negishi M and Philpot RM (1988) Primary sequences of multiple forms of cytochrome P-450 isozyme 2 derived from rabbit pulmonary and hepatic cDNAs. Mol Pharmacol 32: 22–30

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